CABRI is fully dedicated to actively researching new treatments for rare diseases. To support this endeavor, we offer research grants to specific principal investigators at academic research institutions who have a plan to extend the clinical or pre-clinical development of our mission.

Eligible applicants include domestic and international researchers alike, as well as domestic and international group collaborations. Research grants are open to investigators of any career stage who are capable of leading an independent research study and supervising personnel. Funds must be used solely for research. CABRI does not fund institutional overhead costs.

Applications may be submitted at any time during the year.

To apply for a CABRI research grant, please use our Research Proposal Application.

2022 Grant Recipients

$69,500.00 – Miriam Greenberg at Wayne State University –  Evaluation of irisin as a potential treatment for impaired myogenesis in Barth syndrome

$125,214.28 – Laura Goodrich at Colorado State University – Orthopedic Research Center Project Title – KMN159 bone stimulation to enhance fracture repair: a pilot study

$100,000 – Ginger Milne at Vanderbilt University –  Characterization of the SPM Metabolome for the Accurate and Complete Assessment of Endogenous SPM Formation

$71,500.00 – Sven-Erik Dahlen at Karolinska. The study tests the hypothesis that mast cell-dependent bronchoconstriction in subjects with asthma is abolished by the combined inhibition of histamine, cysteinyl-leukotrienes, and PGD2.

$75k-Dr. Craig Wheelock at the Karolinska Institute, Research entitled: “Inhibition of the soluble epoxide hydrolase to treat acute respiratory distress syndrome (ARDS) in COVID-19 patients”.

2021 Grant Recipients

$74,855- Maria do Carmo Pereira da Costa, Research entitled: “NIK as a therapeutic target for Spinocerebellar ataxia type 3.”

Additional $100k to Sven Erik and his team, Research entitled: “Blocking the prostaglandin component of mast cell-dependent bronchoconstriction.”

$50k-Dr. Stefan Zwingenberger at the Center for Translational Bone, Research entitled: “Joint and Soft Tissue Research for Functionalization of biomaterials with KMN-159 to enhance bone quality in an osteoporotic drill hole model in rats.”

$75k-Dr. Floyd Chilton at the University of Arizona, Research entitled: “Impact of Circulating Secreted Phospholipase A2 Group IIA on COVID-19 and ARDS Pathogenesis, Organ Failure, and Death.”

$75,757 Dr. Laura Goodrich at Colorado State University, Research entitled: “Evaluation of the use of small novel compounds, KMN159 and KMN224, as osteogenic inducers in horse and sheep cultures” (2020, 2021).

$75k Dr. Marina Holz at New York Medical College, Research entitled: “Characterization of estrogen-mTORC1 signaling network in TSC/LAM (2020, 2021).

$70k Dr. Elias Arner of Karolinska Institute, Research entitled: “Inhibition of prostaglandin D2 biosynthesis: An unmet need in many inadequately treated diseases” (2020, 2021).

2020 Grant Recipients

$75,000- Dr. Sven-Erik Dahlen, Research entitled: “Inhibition of prostaglandin D2 biosynthesis: An unmet need in many inadequately treated diseases.” (2018, 2019, 2020.)

$60,000- Dr. Mike Holinstat, Research entitled: “ML355 regulation of platelet function, thrombosis, and bleeding in HIT” (2018, 2019, 2020.)

$50,000- Dr. Amanda Huber, Research entitled: “Mesenchymal Stem Cell specific Kdm6b regulates heterotopic ossification in Fibrodysplasia Ossifcans Progressiva.”

$15,000- David Aronoff, Research entitled: “Detection of Clostridium septicum alpha toxin by enzyme linked immunosorbent assay in an infection model” (2019, 2020.)

2019 Grant Recipients

$50,000 – Dr. Stefan Zwingenberger, University of Dresden Research entitled: “Enhancement of bone regeneration by functionalization of various bone substitution materials with a novel and potent lactam acetylene EP4 receptor agonist (KMN-159).”